Perspectives for the Use of Neurotechnologies in Conjunction With Muscle Autotransplantation in Children
Blagovechtchenski E, Agranovich O, Kononova Y, Nazarova M, Nikulin VV. Perspectives for the use of neurotechnologies in conjunction with muscle autotransplantation in children. Frontiers in Neuroscience. 2019;13:99. https://doi.org/10.3389/fnins.2019.00099
Muscles autotransplantation is an important way to restore motor activity in case of injury or diseases associated with a loss of muscles ability. One of the typical examples of such pathology is arthrogryposis multiplex congenita (AMC). Arthrogryposis is one of the most serious congenital malformations of the musculoskeletal system. It is characterized by the presence of two or more major joint contractures, muscle damage, and motoneuronal dysfunction in the anterior horns of the spinal cord. One of the main problems that determines the limitation or even impossibility of self-care of patients suffering from arthrogryposis is the lack of active movements in the upper limb joints, which can be restored by autotransplantation of the muscles of various donor areas (Hall, 1997; Bamshad et al., 2009; Loeffler and Lewis, 2016).